Sweat patches and leukoplakia are common clinical manifestations of lichen planus and vitiligo. Vitiligo and lichen planus are both common dermatological diseases and are often confused at the onset because of certain similarities that may occur in disease symptoms. However, there are certain differences in etiology, clinical manifestations, treatment methods and clinical test results: 1. Etiology: the appearance of sweat patches in patients is usually related to the environment, such as being exposed to sunlight frequently in summer, which may lead to sweaty and humid local skin in patients, and may cause sweat patches to occur if not treated in time. The appearance of white spots is often related to family genetics, impaired immune system, nervous tension and other factors; 2, clinical performance: sweat spots are commonly located in the trunk, upper arm, neck, armpit and other parts of the patient, usually symmetrical distribution, manifested as purple, tan, pink, white or brown rash, often about 4-5mm in diameter, after scratching there can be scales, occasionally visible itching. White spots may occur in any part of the body, and the skin damage is mainly manifested by pigment loss white spots of varying color and shape, usually without other color rashes, and usually without itchiness and other symptoms; 3, treatment methods: at present, sweat spots are mainly treated by medication, which can be applied topically with dilute hydrochloric acid, glacial acetic acid, salicylic acid and other drugs, or using terbinafine, ketoconazole, bifenoconazole and other types of drugs for treatment. The antibacterial treatment can be carried out with drugs such as terbinafine, ketoconazole, bifenazole, etc. to control the appearance of sweat spots. Patients with leukoplakia can be treated with a combination of medication, physical therapy, and surgery. If the symptoms cannot be relieved by medication, it can be treated by ultraviolet irradiation, laser or surgical implantation; 4. Clinical test results: microscopic examination of the skin flakes of sweat spots can find short rod-shaped mycelium or clusters of round or ovoid spores. The white spots are not caused by fungal infection, usually no scales are shed, and the fungal test is negative. If patients have spots on the skin, they should visit the dermatology department of the hospital for consultation due to individual differences, make a comprehensive judgment through the examination results and actively carry out treatment.