Recently, Granny Wang, who is nearly 70 years old, finally showed her long-lost smile, as if she was back to her previous state, much younger and happy as a child. Wang held the doctor’s hand tightly and was indescribably grateful. It turned out that Wang had a problem called facial muscle twitching 20 years ago, initially only the left upper eyelid twitching, as the saying goes: the left eye jumping money, the right eye jumping disaster, has not been taken seriously. The condition did not end here, but the left corner of the mouth, the face and even the neck all had paroxysmal twitches one after another, and the degree of twitching was getting heavier and heavier. She became agitated, nervous, often had insomnia, and was exhausted all day long, like a different person. For many years, Wang has been seeking medical treatment, and has taken antiepileptic drugs such as carbamazepine and phenytoin sodium, but her condition has hardly improved, and she has also tried local facial injections of botulinum toxin, which had some effect at first, but her condition relapsed in less than 3 months. In fact, Wang’s disease is medically known as facial muscle spasm, mostly seen in middle-aged and elderly women, mainly manifested as involuntary twitching of one side of the face. The typical facial muscle spasm usually starts from the eyelid and gradually expands down the face, with symptoms worsening during mood swings, fatigue and insomnia. If not treated effectively, facial muscle twitching has a tendency to gradually worsen, and in severe cases, eating and seeing will be affected, and the person will become irritable, irritable and hypersensitive. So is there a way to treat facial muscle spasm? The traditional concept is that facial muscle twitching is similar to epileptic seizures, and some anti-epileptic drugs can be taken, but clinical practice has found that anti-epileptic drugs have almost no effect on facial muscle spasm. Later, it was discovered that Botox could block the nerve conduction between the nerve muscles, and local injection of Botox facial could help to relieve the symptoms, but Botox also destroyed the normal nerve conduction at the same time, producing facial paralysis, and when the facial paralysis recovered the symptoms recurred, and long-term injection of Botox could easily lead to permanent facial paralysis and new problems. In recent years, with the development of medicine, people found that facial muscle spasm is mainly due to intracranial facial nerve compression by blood vessels. Microvascular decompression of the facial nerve is performed through minimally invasive microsurgical methods to isolate the facial nerve from the compressing blood vessels without damaging the facial nerve and blood vessels, which has achieved satisfactory results and gradually become the preferred method for treating facial muscle spasm. On the first day after the surgery, Wang’s facial muscle twitching symptoms disappeared completely, and she finally got rid of the long-term disease and started a new life again.