With the increasing maturity of IVF technology, more and more people are joining the ranks of “IVF” for pregnancy. Mothers-to-be undergoing IVF treatment undergo intense ovulation treatments and painful egg retrieval procedures, followed by embryo transfer. After seeing the baby embryos being transferred into the uterine cavity, the mothers-to-be are worried about whether the embryos will flow out of the uterine cavity. Can they still urinate easily? Will they be able to climb stairs and go to work? Some people take 2 weeks of bed rest after embryo transfer, is this necessary? These and other questions are really troubling for mothers-to-be. Here I will briefly tell you about the precautions after embryo transfer. A relaxed and happy mood is a prerequisite for success Needless to say, infertility itself brings great psychological stress to both couples. The lack of understanding of IVF technology and the uncertainty of future outcomes invariably add to the psychological burden of infertile couples. Scientists have found that about 20-30% of women undergoing IVF treatment suffer from anxiety and depression. It is evident that anxiety and depression are a common phenomenon among couples undergoing IVF treatment. Anxiety and depression can have an impact on pregnancy outcomes in IVF by affecting hormonal or immune system stress mechanisms. Some scholars have even found that the endometrium secreted significantly lower levels of regulatory fertility factors during the fertile period in patients who were mentally stressed than in those who were mentally relaxed. It is evident that mental stress, anxiety and depression are harmful rather than beneficial to patients. Therefore, the first precaution in performing embryo transfer is to relax and adjust your mind well. In fact, there is no need to be overly nervous. After years of innovation and improvement, IVF technology is gradually maturing, and the success rate of one cycle of IVF has increased to 40%-50%, and the success rate of frozen-thawed embryo transfer has also reached 30%-40%, with a cumulative success rate of 60%-80%. The vast majority of women get what they want after several cycles of treatment. Therefore, it is important to have enough confidence in IVF technology and believe that you can succeed. For those who have failed, there is no need to be discouraged, but to embrace another treatment with the mindset of starting over. Secondly, learn to relax yourself and take the initiative to regulate your mood. Although the treatment process is tedious, but do not take it as a heavy burden, after the treatment, you can read more relaxing books, watch more fun movies, or go to nature to relax. Family members should also try to create a harmonious and relaxing atmosphere for them. In short, a relaxed mood and a calm mind are most conducive to the conception and birth of a new life. Second, on-time medication is the guarantee of success Progesterone is needed for luteal support after the transfer. This is because during the ovulation promotion process before embryo transfer, in order to control the timing of ovulation, some medications are often used to prevent the body from producing a spontaneous luteinizing hormone peak (i.e. spontaneous ovulation) to appear, and these medications can affect the development of the corpus luteum. In addition to this, the egg retrieval process aspirates a large number of granulosa cells along with the eggs, which reduces the number of granulosa cells and leads to luteal hypoplasia. Therefore, luteal support is required. Luteal support is usually performed using progesterone injections, suppositories used vaginally or anally. Progesterone injection is a traditional drug with stable effect, but as an oil, it is difficult to be absorbed after injection and tends to form lumps at the injection site, causing pain and other discomfort. Suppositories used vaginally and anally are well absorbed and reliable, but their high price limits their widespread use. Regardless of which drug is used, it is important to cooperate with the doctor and take the medication on time to ensure that the endocrine environment in the body is suitable for the conception of new life. The so-called embryo transfer is a tiny tube that transports the embryo into the uterine cavity and will not fall out when urinating, defecating or exercising. So don’t hold your urine after the transfer because you are afraid of the embryo flowing out of the uterine cavity. Otherwise, the filled bladder will compress the uterus and cause contraction of the uterus; and the urethra of women is very short and close to the vaginal opening, so urinary tract infection will easily occur after the surgical operation. Patients are advised to drink more water and urinate more after transplantation to flush the urethra and reduce the chance of urinary tract infection. Bed rest for half an hour to one hour is usually sufficient after transplantation. There is no need to worry about which position is good, it is enough to be relaxed and comfortable. Scientists have found that engaging in a moderate amount of labor after transplantation is beneficial for embryo implantation and increases the pregnancy and live birth rates. However, due to the increased size and weight of the ovaries during ovulation promotion, excessive exercise or rotational exercises are not recommended to prevent ovarian torsion. In fact, few people engage in heavy exercise after transplantation, so it is essential to encourage patients to walk or perform moderate exercise activities. In addition, it is recommended to continue working at work after transplantation. This will divert attention from having to dwell on the worry of whether or not you can get pregnant, allowing the body and mind to fully relax, thus helping to improve the success rate of IVF. IV. Can I have sex after embryo transfer? Traditionally, it is often recommended that patients should not have sex after transfer. However, scientists have found that patients who had sex 2 days before or 2 days after the transfer had an increased rate of embryo implantation. The reason for this is due to the fact that certain components of the semen can initiate an immune response and increase the embryo implantation rate. Given the increased volume and weight of the ovaries during the ovulation promotion cycle, sexual intercourse should be temporarily avoided in the case of ovarian volume overload to avoid ovarian torsion. If the ovarian volume in the ovulation promotion cycle is not large, or in the frozen embryo transfer cycle, it is possible to have sexual intercourse. When the fertilized egg is laid, i.e. on the 3rd-4th day after transfer (or on the 1st-2nd day after blastocyst transfer), the embryo has differentiated to form the trophectoderm, and the chorionic gonadotropin (HCG) starts to be secreted by the chorionic trophoblast cells, which can be measured in the serum after about 1 day. HCG secretion increases rapidly in early pregnancy, doubling in size in about 2 days. Since HCG is water-soluble and easily absorbed into the blood, it can be detected by radioimmunoassay 8-9 days after transplantation and can diagnose early pregnancy. HCG can be detected in urine about 14 days after transplantation, so blood HCG is usually checked 14 days after transplantation to clarify whether pregnancy is present. Individual women experience a small amount of vaginal bleeding after transplantation, but this does not indicate non-pregnancy. Blood HCG must be checked for a clear diagnosis to avoid stopping progesterone application on their own, which can cause a drop in progesterone levels and lead to miscarriage findings and lifelong regrets. If pregnancy is confirmed to be obtained, progesterone is to be continued for luteal support. Progesterone dosage should be gradually reduced after 7 weeks of gestation when the placental tissue is formed and can secrete progesterone. In addition to the above five points, after embryo transfer, avoid going to crowded places with poor air circulation; add clothes in time when encountering weather changes to avoid infectious diseases such as cold.