The main causes of unresponsiveness and memory loss are physiological factors, anxiety disorders, depression, and dementia, as follows: First, physiological factors: physiological factors are due to long-term insomnia, poor rest, and fatigue, patients subjectively feel that they will have unresponsiveness and memory loss, but if cognitive function tests are performed, they are often normal. Second, anxiety disorders, depression: anxiety disorders, depression patients can also appear the above phenomenon, their slow reaction, memory loss, through antidepressant, anti-anxiety treatment, with psychological counseling, with the improvement of anxiety, depression, the patient’s slow reaction, memory loss phenomenon can be reduced. Third, Alzheimer’s disease: early stage of Alzheimer’s disease will show slow reaction and memory loss, and at this time there will also be language dysfunction and visual space disorder, which need to take drugs such as donepezil and carboplatin for treatment.