In advanced nasal NK/T-cell lymphoma, radiotherapy and chemotherapy should be combined 1. If the advanced nasal NK/T-cell lymphoma has invaded other parts of the body, is radiotherapy alone not enough? Does it require a combination of radiotherapy and chemotherapy? A: Chemotherapy is the main treatment for advanced patients, and radiotherapy can be used for tumor sites that are insensitive to chemotherapy or have obvious residual. 2.Does the integrated treatment require radiotherapy first and then chemotherapy? A: Chemotherapy is preferred for advanced stage patients, which can control the lesions that have spread to the whole body. For tumors that do not have significant effect of chemotherapy, radiotherapy can be combined with it. 3.How many times do I need radiotherapy in general? According to what? A: As mentioned earlier, the dose of radiotherapy usually reaches 50GY, which is about 25 times in total. The dose is mainly determined by the location of the lesion, the remission of the tumor during radiotherapy, and the patient’s tolerance and other factors. 4.What is the general regimen of chemotherapy? How many courses of treatment are needed? A: There is no uniform chemotherapy regimen. It usually consists of 3-4 drugs that are proven to be relatively sensitive to NK/T-cell lymphoma, such as: levomepromazin, methotrexate, gemcitabine, platinum, pedialyte glucoside and isocyclophosphamide. The number of treatment courses varies from 4 to 8 cycles depending on the efficacy and the patient’s physical condition. 6.What is the effect of combined radiotherapy and chemotherapy? Can the patient’s self-perceived nasal symptoms and high fever symptoms be relieved? A: Most of the patients can have rapid tumor regression and symptom relief after chemoradiotherapy. 7.Can the combination of radiotherapy and chemotherapy cure the advanced NK/T-cell lymphoma? How long can the survival period be extended? A: Some advanced NK/T-cell lymphoma can achieve long-term remission or even cure by combined chemoradiotherapy.