In patients with adenomyosis, the uterus enlarges mainly because the endometriosis lesion is ectopic in the myometrium, and every time the endometrium sheds and bleeds during menstruation, the ectopic lesion also bleeds in the myometrium, and small cystic echoes are formed locally over time, which gradually increase and lead to an enlarged uterus, increased menstrual flow and In about 50% of patients, infertility is also present. Patients with adenomyosis can be treated with the Mannakil ring or with Vesanine, both of which are effective. It is recommended that these patients eat less estrogen-containing foods, such as soy milk and royal jelly, in their daily lives.