The current progress in the treatment of anejaculation is limited, and the treatment of premature ejaculation is good, as discussed in the following classifications. 1. Anejaculation (anejaculation): a classification belonging to delayed ejaculation (DE), which refers to the absence of semen ejaculation during sexual intercourse, including the absence of semen overflow and non-ejaculation, and the sense of orgasm may or may not be present. Primary ejaculation can be due to brain or nerve damage, testicular dysplasia, androgen deficiency, and obstruction of the seminal tract; secondary ejaculation is often due to psychological factors (sexual fears, sexual aversions, etc.), and drug effects. Drugs for DE have made limited progress; ephedrine, etc. may be effective. Psychological factors should be channeled/intervened under the guidance of a medical professional. 2. Premature ejaculation (PE): Premature ejaculation is a short intravaginal ejaculation latency time (IELT) (<1 minute) during sexual intercourse. PE should also be treated with clear etiology (endocrine disease, mental/psychological disorders, vascular disease, etc.). Treatment of PE with non-pathologic lesions includes general treatment (smoking cessation, exercise, etc.), psychotherapy, and pharmacotherapy (dapoxetine). Pharmacotherapy is more effective as a first-line treatment for PE (prolonging ejaculation time by more than 2.5 times). To summarize, regardless of the disease, you should seek medical treatment as early as possible and follow your physician's instructions to avoid delays and improve your quality of life. The application of the above drugs should be applied under the guidance of a professional physician.