Patients are not advised to touch water at the site of the needle eye for 24 hours after the vaccination because bacteria in the water may enter the body with the needle eye and cause a local infection. If water is touched outside of the needle site, it usually has no effect on the body. If this wound comes into contact with bacteria in the water, the bacteria may enter the body and cause local infection, redness, swelling, heat, pain and other symptoms, and even fever and other systemic symptoms. Patients who experience the above-mentioned conditions should seek medical treatment for anti-infection in a timely manner at a regular hospital to avoid delays. However, since the eye of the needle is small after vaccination, even if the patient accidentally gets wet, the probability of bacteria in water entering the eye of the needle and causing infection is very small, so it is enough to pay attention to observation, and if there are no other symptoms, such as redness, swelling, heat and pain, there is no need to worry. Patients may experience mild fever, abdominal pain, local redness, rash and other adverse reactions after vaccination, which generally do not require special treatment and will recover on their own after a period of time. In addition to not getting water in the eye of the needle after vaccination, patients should also avoid drinking alcohol, minimize the consumption of spicy, stimulating and greasy food, and avoid strenuous exercise and staying up late.