Patient: Hello! Dr. Jiang: When I saw you on August 14 this year, I was already 5 weeks pregnant, and the result of blood test: T3 was 3.00, T4 was 1.42, thyrotropin was 1.457, and thyroglobulin antibody was 28.2. At that time, you told me to take only one kind of PTU medicine, and the dosage of the medicine was once a day, one capsule each time, and the other medicines were not eaten for the time being, including cystine, eugenol, vitamin B1, and a kind of medicine which seems to be heart type. I forgot the name of the drug, and told me to go for blood test after two weeks. I went for blood test on September 2, and the result was T3 was 3.43, T4 was 1.21, thyrotropin was 0.30, thyroglobulin antibody was 36.7, and thyroid peroxidase antibody was 259.0, which means that the thyrotropin was a little bit low, so how do I take my medication? Thank you. Jiang Ningyi, Department of Nuclear Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University: Keep taking it, no need to reduce it. Patient: Hello! Dr. Jiang: I read in a book that propylthiouracil tablets can cause congenital enlargement of the thyroid gland in newborns if they are taken during pregnancy, is this true? Is it true? Besides, will this medicine have other effects on the fetus, such as affecting intelligence or other aspects? Mr. Jiang Ningyi, Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University: There should be no problem. Generally speaking, small doses of PTU have no effect on the fetus. Patient: Hello! Dr. Chiang: So will I go for blood tests every two weeks from now on to see the dosage? I went for two blood tests on August 20 and August 27, and the progesterone levels were 23.98 and 22.90 respectively. The gynecologist said that both levels were low, so I was afraid that I might miscarry easily and asked me to take a progesterone injection, which is also caused by hyperthyroidism, right? Besides, can I take autumn ginseng in this situation? Because I heard that autumn ginseng is good for keeping the fetus alive. Thank you! Jiang Ningyi, Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University: It should not be directly related to hyperthyroidism, respect the gynecologist’s opinion. Patient: Hello, Prof. Jiang. My son was born on April 2, thank you very much for your help. I had a blood test on April 1, in which T3:2.8 T4:0.93 TSH3: 1.093 aTG: 32.2 And my thyroid function during pregnancy was normal, I have been taking a PTU tablet every day according to what you said, and I would like to consult you, do you want to do any tests for my baby? If so, how old should I go? I am not breastfeeding, I am taking formula milk. Jiang Ningyi, Department of Nuclear Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University: Congratulations on having a healthy boy. Children usually have no problems, just check that there are no problems at birth. It can be breastfed and should be breastfed. PTU can reach breast milk through the mammary glands, but the amount is very small. Studies have shown that the amount of PTU in all milk at 24 hours is 0.07% of the amount taken by the mother. Mothers take PTU 200mg 3 times a day and pediatricians get 99ug daily. therefore, breastfeeding is safe. The World Health Organization also suggests that mothers can breastfeed with PTU.