There are several possibilities for thigh root melanin deposition:
1, eczema: Repeated irritation after inflammation causing hyperpigmentation;
2, ringworm: Repeated episodes causing hyperpigmentation;
3, pseudoacanthosis nigricans: Also known as pigmented papillary dystrophy, a rare skin condition characterized by deepening skin color and papillary or velvety thickening, manifesting as neck It is characterized by grayish-black velvety thickening and pigmentation of the neck, axillae and inguinal folds.
4. Hyperpigmentation caused by acanthosis nigricans is not completely clear, and multiple causes stimulate tyrosine-free growth factor receptor signaling channels in the epidermis, but there is evidence that insulin plays a role;
5. The incidence of acanthosis nigricans in women with androgenemia is high, and obesity is strongly associated with acanthosis nigricans in a positive correlation. Or other factors such as. Topical topical keratolytic agents such as carboxytriol and salicylic acid, vincristine ointment, etc. In recent years, the widespread use of laser also has good effect, you can choose a variety of laser treatment such as CO2 fractional laser. Acanthosis nigricans should be investigated for diseases such as tumors and diabetes and aggressive treatment of the primary cause, and weight loss is also a good approach.