Acute cholecystitis is a relatively common clinical condition of the gastrointestinal tract, usually caused by bacterial infection. The disease generally has an acute onset, with the typical symptoms being sudden onset of abdominal pain and possibly nausea, vomiting and other gastrointestinal symptoms. The treatment principle is generally anti-infection, release the biliary tract spasm, treatment can be conservative drug treatment or surgery: a. Symptoms: 1, abdominal pain: usually manifested as a sudden onset of right upper abdominal or epigastric pain, mostly paroxysmal colic, more obvious after a full meal, high-fat greasy diet and at night. Pain can also radiate to the right shoulder, and pressure pain can appear in the right upper abdomen; 2, gastrointestinal symptoms: often accompanied by nausea, vomiting, abdominal distension, acid reflux, heartburn and other gastrointestinal symptoms; 3, fever: mostly mild to moderate fever, if chills, high fever and other deteriorating performance, suggesting that the condition may be aggravated, such as the occurrence of septic gangrene, perforation of the gallbladder; 4, other: some patients may also have generalized skin jaundice, sclera yellowing and other manifestations. Scleral yellowing and other manifestations. Treatment: 1, general treatment: patients with acute cholecystitis should fast, vomiting, abdominal distension patients can be gastrointestinal decompression, and the need for timely intravenous rehydration to correct electrolyte disorders; 2, drug therapy: often take antibiotics for anti-infective treatment, mostly cephalosporins, such as ceftazidime, ceftriaxone. Severe infections can be applied according to the condition or drug sensitivity test results of carbapenems, such as ertapenem, meropenem, etc.. Belladonna tablets and ursodeoxycholic acid tablets are also commonly used to achieve antispasmodic and pain relief, anti-inflammatory and biliary effects. Liver-protective drugs and nutritional support drugs can be used when necessary; 3. Surgery: For recurrent attacks, or acute cholecystitis with gallbladder stones, cholecystectomy is generally required. For patients with septic cholecystitis who are critically ill and not suitable for surgery, percutaneous transhepatic cholecystocentesis and drainage is required first, and then elective surgery.