Ischemic necrosis of the femoral head in children

  Ischemic necrosis of the femoral head in children, also known as osteochondrosis of the femoral head, aseptic necrosis of the femoral head, Perthes disease, and juvenile deformational osteochondritis of the femoral head. In terms of its etiology, pathology, symptoms, treatment and prognosis, it is different from that of adults, and it is a self-healing disease with a slow course. The incidence varies from region to region, and the incidence in China is about 1 per 1,000. It is mostly seen in children aged 4-10 years old, with a male to female ratio of 4:1, of which 10% are bilateral.  Etiology: The true etiology of this disease is not fully understood. At present, it is mainly thought to be related to the following factors: 1. Infectious factors: Due to the infection of the hip joint, the pressure in the joint capsule increases, which leads to venous stasis in the joint capsule, poor blood return, impaired blood circulation in the femoral head, and ischemic necrosis occurs. 2. Congenital factors: Many scholars have found that there are congenital anomalies and defects in the nutrient vessels of the femoral head in children, especially in boys. 3. Genetic Endocrine factors: It was found that the growth hormone mediator in the plasma of the affected children is significantly lower than that of normal children of the same age, and the growth hormone mediator in the blood of normal boys is lower than that of normal girls, so the disease is more likely to occur in boys. It is found that more children are obese, which may be related to the greater gravitational force on the femoral head.  Symptoms: The onset of the disease is slow and the duration of the disease is long. Intermittent claudication and pain occur over several months, and the pain often radiates to the knee and inner thigh. Some children have knee pain at the onset of the disease, but hip symptoms are not obvious. The symptoms of claudication and pain may increase with activity and decrease with rest. The hip joint has an abduction deformity with limited abduction and internal rotation. Some children may be asymptomatic or have mild symptoms in the early stages. There are three important clinical signs, namely obesity, reduced range of motion of the hip joint, and tightness of the intraskeletal muscles. The main manifestations on X-ray are increased density, small size, cystic degeneration, fragmentation of the femoral head, and widening and shortening of the femoral neck.  Treatment: Different treatment methods should be used according to different pathological stages, and the commonly used treatment methods are non-surgical therapy and surgical therapy. Non-operative therapies include traction, hip herringbone cast fixation, and weight-free brace. Surgical treatment includes drilling and decompression, tipped muscle graft, intraosseous vascular bundle graft, vascular bundle graft, synovectomy, periprosthetic muscle release, osteotomy, etc.  Prevention: Since the cause of this disease is not clear yet, there is no reliable preventive measure. However, attention to the following aspects can have a positive effect on the prevention of this disease.  ①When children have abnormal gait for unknown reasons, they should go to a specialized hospital as early as possible for early detection and treatment.  ②For children with hip synovitis, they should be treated thoroughly to prevent recurrence because some cases can turn into ischemic necrosis of the femoral head.  ③Children who are too obese should lose weight.  ④Discontinue marriage between close relatives.  Prognosis: ①The prognosis is good at young age, and those who develop the disease under 6 years old have few sequelae.  The prognosis for girls is poor, mainly because the skeletal maturity of girls is earlier than that of boys, so the shaping time is shorter.  The prognosis is poor for those who develop pathological changes during the treatment and observation process.  ④The prognosis is poor for those who have already developed hip subluxation or dislocation at the time of consultation, and whose hip movement is obviously restricted.  If your child is suffering from ischemic necrosis of the femoral head or has similar manifestations, please take your child to the pediatric orthopedic department of a specialized hospital for early detection, early diagnosis and early treatment, so as to obtain a better treatment effect and minimize the sequelae.