The drugs for the treatment of uremic patients with high blood pressure are renin-angiotensin-aldosterone receptor antagonists, calcium antagonists, diuretics, beta-blockers, and alpha-receptor antagonists. 1. Renin-angiotensin-aldosterone receptor antagonist: the drugs that can be chosen are captopril, benazepril, valsartan and so on. These drugs are suitable for uremia with high blood pressure, but the adverse effects are large, may cause blood creatinine, blood potassium increase. 2. Calcium antagonist: optional drugs are nifedipine, amlodipine and so on. The common adverse reactions of this kind of drugs are flushing, tachycardia and so on. If serious adverse reactions occur, the drug should be stopped promptly. 3. Diuretics: optional drugs include furosemide, hydrochlorothiazide, etc., which can reduce blood volume by promoting the body’s drainage of sodium, but long-term application can lead to ionic disorders, hyperuricemia and so on. 4. β-blocker: optional drugs include bisoprolol, metoprolol, etc., which can lower blood pressure by slowing down the heart rate and decreasing the contractility of the heart, but excessive use of this drug may cause sinus bradycardia. 5. α-receptor antagonist: common drugs for prazosin, terazosin, etc., the drug can cause rebound hypotension, the first oral, it is recommended to take at bedtime, pay attention to monitor blood pressure changes. All of the above drugs should be used in accordance with medical advice, do not self-medication. Uremic patients are advised to go to the regular hospital in time, under the guidance of the physician standardized treatment.