There is a special group of patients in obstetrics and gynecology clinics who have had several successful pregnancies and several forced miscarriages. Why? Because the sac in the uterus is empty, and the heart tube always fails to beat with a flash of light under the ultrasound, so close to the baby but always fails to see him, how to find the cause next? Read the following text, maybe you can take a detour less.
1.Chromosomal abnormalities.
Ⅰ, embryonic chromosomal abnormalities (in the event of an unavoidable miscarriage, the embryonic villi are taken for chromosomal examination when clearing the uterus, and fresh villi tissue is required.
Ⅱ, couple chromosomal abnormalities.
2.Endocrine abnormalities.
Ⅰ, polycystic ovary syndrome (blood sampling for sex hormone measurement from the third to the fifth day of menstruation, self-testing basal body temperature every month and gynecological ultrasound after menstruation is clean)
Ⅱ, hyperthyroidism or hypothyroidism (thyroid hormone test, not affected by menstrual cycle)
Ⅲ, hyperprolactinemia (can be measured after 15 minutes of sitting still without fasting around 9:00 a.m., not affected by menstrual cycle)
Ⅳ, diabetes mellitus/insulin resistance (fasting blood glucose and insulin, oral glucose followed by blood glucose and insulin)
V. Luteal insufficiency (self-measurement of basal body temperature each month)
VI, ovulation disorder (ultrasound monitoring of follicle development to follicle discharge after the 12th day of menstruation)
3.Anatomical abnormalities of the reproductive system
I. Uterine adhesions (ultrasound, hysteroscopy, hysterosalpingography, which can be performed immediately after menstruation)
Ⅱ, uterine malformation (ultrasound, hysteroscopy, hysterosalpingography, etc.)
Ⅲ, cervical insufficiency (cervical dilatation test, ultrasound, imaging, etc.)
4.Infection factors
I. Mycoplasma, Chlamydia, etc. (cervical mucus is taken, non-menstrual period)
Ⅱ, TORCH, HIV, RPR, etc. (blood can be drawn at any time)
5.Thrombotic factors
Ⅰ Congenital pre-thrombotic state (coagulation factor V mutation, prothrombin gene mutation, protein C defect, protein S defect, homocysteine, prothrombin III activity.)
ⅡAcquired pre-thrombotic state (anti-cardiolipin syndrome: requires repeated blood sampling about 3-5 times, each time about one month apart, without fasting; platelet aggregation requires fasting)
6.Immune factors
I, autoimmune type (anti-cardiolipin syndrome: requires repeated blood draws 3-5 times, each time a month apart, not related to the menstrual cycle)
7.Uterine blood supply factors
I. Pregnancy: uterine artery at 6-7 weeks of early pregnancy / 12 weeks of middle pregnancy; ultrasound examination of umbilical artery at 20 and 30 weeks of pregnancy
8, male side examination: semen full set (abstinence 3-5 days to check semen)
In addition to the above factors, there are many uncertainties that cannot be detected by medical means at present. After so many examinations, we can find the cause of the disease for each patient and give the right treatment for the cause.