Patients with acute myelitis may die of respiratory failure within days of onset, may survive for weeks or months, or may survive for years, and patients may survive for decades, depending on the extent of the lesion and the presence of comorbidities. If the lesion involves a long segment of the spinal cord, and if the lesion is diffuse, the patient may present with complete paralysis, and in most cases, the electromyogram shows loss of nerve changes 6 months after the onset of the disease, and the prognosis is generally poor. Most patients may have sequelae or die from complications. If patients do not have serious comorbidities, most of them can return to basic self-care 3-6 months after the onset of the disease. If the patient has a combination of decubitus infection, pulmonary infection and urinary tract infection, it may affect the patient’s treatment outcome. Acute myelitis usually has an acute onset and is serious, and the patient should be given the correct treatment in a timely manner after the onset.