As a third world country, the prevalence of H. pylori infection in adults in China is close to 50% and increases with age. However, not all patients with H. pylori infection (including positive breath test, positive rapid urease test, and positive silverophilic stain test) require H. pylori eradication. Those who are recommended for eradication treatment are those who have Hp infection in combination with: 1. definite upper gastrointestinal symptoms; 2. family history of gastric cancer in first-degree relatives (parents, siblings, children); 3. existing ulcers or history of previous ulcers; 4. definite more severe chronic or acute gastritis; 5. long-term use of acid-suppressive drugs for more than 1 year, or plan to take acid-suppressive drugs for more than 1 year; 6. having High risk environmental factors for gastric cancer (heavy smoking, long-term exposure to dust, coal, quartz, cement or quarry workers); 7. Those who have a high incidence of gastric cancer where they live and are worried about the occurrence of gastric cancer. adolescents under 13 years of age generally do not need H. pylori eradication treatment unless they have an established disease related to H. pylori infection This is mainly because of the following points: 1, children have a high recurrence rate after eradication and are likely to be reinfected as they grow older; 2, antibiotics interfere with the intestinal microecology and are detrimental to the establishment of immune function for normal development of the digestive tract in children; 3, antibiotics have other safety risks.