Drooling from the corners of the mouth and slanting of the corners of the mouth are among the most common precursors of cerebral thrombosis, in addition to symptoms such as dizziness, rotation of vision, weakness and numbness of the lateral limbs, and unsteadiness in walking. If the symptoms are not treated in time, they may gradually worsen and lead to different degrees of speech dysfunction, hemiplegia, choking and coughing, difficulty in swallowing, and even death in severe cases. Therefore, cranial CT, MRI and other auxiliary examinations should be performed in hospital in time, and rtpa or urokinase intravenous thrombolysis, antiplatelet drugs (such as aspirin, clopidogrel, indomethacin, etc.), statins (atorvastatin, rasulvastatin), circulation improving drugs (thromboxane, ginkgo biloba preparation) and free radical scavenging drugs (edaravone, cytarabine, etc.) should be given as early as possible. In case of severe intracranial and extracranial arterial stenosis, emergency stenting or endovascular stenting is indicated. Acupuncture, physiotherapy, rehabilitation, and exercise therapy can also be given after the disease is stabilized to reduce the occurrence of sequelae.