Skin diseases and depression are generally felt to be unrelated. Liu Dongmei, the chief Chinese medicine doctor, reminded that many skin diseases can not be cured, but turn a thought, starting from depression treatment, there will be unexpected results. One, Liu Dongmei said, four or five years ago, a 30-year-old female patient, was admitted to the hospital with facial seborrheic dermatitis. She said she could not wash her hair, as long as she washed her face red and itchy, at first she thought it was due to allergy to shampoo, so she switched to soap, but the situation did not improve a bit, the same allergy to the face. Later, she wondered if it would be better to use cold water, so even in the cold winter, she washed her hair with cold water, not daring to use a little hot water, but the situation remained the same. Because of the severity of the allergy, she could not go to work, so she was hospitalized and wanted to thoroughly investigate what was the cause. After listening to the female patient, Liu Dongmei felt that it should be a mental problem, but the female patient insisted that she was an intellectual and had knowledge in this area, so it was impossible that she could not even distinguish between skin disease and mental illness. After a complete examination and the corresponding skin treatment to no avail, the female patient found Liu Dongmei again, saying that she really had no fold, every time after the skin treatment looked like the effect, but as soon as the hair was washed back to its original shape, repeatedly. This disease has been tormenting her for six or seven years, so she can’t stand it anymore. Liu Dongmei suggested that she bring her family along, she said her husband was working abroad and could not come, only her mother could come with her. In this way, mother and daughter found Liu Dongmei once again. Liu Dongmei said to the mother, from experience, your daughter’s disease should be a mental problem, which is caused by high neurovascular sensitivity (once you wash your hair, you will be nervous, a nervous vascular nerve sensitivity is increased, you will secrete a lot of, neuromediators, inflammatory mediators such as histamine, leukotrienes, 5-hydroxytryptamine, etc., the patient will have a facial redness, itching, burning sensation, it is recommended that its first to the psychiatrist for treatment. After anti-anxiety and anti-depressant treatment, this female patient was surprisingly cured of her persistent illness for many years. ”Starting from this case, I kept an eye on it and found that this type of patient is increasing year by year.” Liu Dongmei put it this way. Second, according to Liu Dongmei, depression is a mood disorder psychosis. According to statistics, the prevalence rate is as high as 6-17%, and it is called “the ‘cold disease’ of mental illness”. The disease is often chronic and recurrent, with a recurrence rate of 60% within 5 years after recovery from major depression, 75% within 10 years, and a lifetime prevalence of 5.8%. According to the survey, half of the depressed patients can be accompanied by other somatic diseases, and skin disease is one of them. Although depression is now widespread, depression in patients with dermatological disorders usually goes unnoticed. Like a female driver in her 40s who was seen the other day, her face was full of red spots and papules, red and itchy and blistered, and later developed into itchy all over her body, making it difficult to sleep at night. She couldn’t be treated as a skin disease. Later, her husband reminded her with a casual remark, “You are not depressed again, are you? As a result, after antidepressant treatment, all her symptoms were relieved in just one week. Liu Dongmei said, clinically, there are many patients similar to this female driver, which looks like a typical skin disease and is missed or misdiagnosed as a result. Therefore, doctors must talk to patients more often when they are seen to see if they have anxiety, insomnia, have been stimulated, etc., in order to clarify the diagnosis and make the treatment less of a detour. There are also some patients, from the conversation can be seen some mental aspects of the problem, such as patients say, there are bugs crawling on the body, very itchy or say that the skin in the blood in the poison, have to pick dig out the blood and so on …… because mental disorders disease can be accompanied by skin hallucinations, suspicious ideas or personality disorders and other kinds of skin manifestations. Third, Liu Dongmei said, can be accompanied by depression of the following skin diseases: baldness, acne vulgaris, atopic dermatitis, chronic simple moss (neurodermatitis), nodular itchy rash, psoriasis, urticaria, seborrheic dermatitis, artificial dermatitis, hair pulling seclusion, nail biting fetish, pruritus and so on. Although these dermatoses are general dermatoses, they are all related to psychiatric factors, so they are classified as neurological and psychiatric dermatoses in dermatology, and there is a high prevalence of depression in this category. Especially when damage to important parts of the body image (scalp, face, breasts, external genitalia), more likely to be accompanied by depression, and the patient’s self-esteem and self-confidence is extremely low, and its severity is sometimes enough to lead to suicide. Reminder: Depression, especially major depression, should be referred to psychiatry for specialist treatment. However, depression with skin manifestations should be adequately treated in the corresponding disease or with in the drug makeup, laser with the basis of repair, find psychiatry for specialist treatment of antidepressants and psychological intervention. Liu Dongmei said that some studies have shown that antidepressants can help treat intractable pruritic dermatoses even if the patient has no psychiatric symptoms. The application of antidepressants to treat intractable chronic urticaria, angioedema, pruritus, pruritic nodular rash, nocturnal itching in the case of atopic dermatitis, post-herpetic neuralgia, and facial reoccurring dermatitis has met with some success. Therefore, we remind our patients that when your doctor gives you a prescription with psychiatric drugs, please don’t make a fuss, your doctor is trying to help you get rid of itchiness soon oh!