Chest pain after drinking is often associated with an irritating reaction to alcohol or the occurrence of angina pectoris or acute myocardial infarction. It is necessary to stop drinking as soon as possible and take general treatment and medication according to the cause. 1. Irritant reaction: If the reaction is caused by the stimulation of gastric mucosa, esophagus and pleural tissues by alcohol, the symptoms will be relieved on their own after stopping drinking, and the alcohol can be metabolized out of the body by vomiting if necessary. 2. Angina: If angina is caused by drinking, it is recommended to use nitrate drugs as soon as possible, such as nitroglycerin and isosorbide nitrate, which can effectively reduce myocardial oxygen consumption and relieve angina. Those who have obvious heart rate increase can take bisoprolol and metoprolol orally to fight arrhythmia. 3. Acute myocardial infarction: If you are suffering from some kind of heart disease, drinking alcohol may suddenly induce acute myocardial infarction, which may lead to chest tightness and pain. At present, it is necessary to absolutely bed rest, and keep quiet, and then regularly monitor the vital signs; severe symptoms, should follow the doctor’s advice to use morphine, pethidine pain, and then sublingual nitroglycerin. If chest pain occurs after drinking alcohol, in order to prevent sudden death after acute myocardial infarction, you need to promptly seek medical attention or call 120 emergency, standardized treatment in accordance with medical advice.