Polyacrylamide Hydrogel (PAHG) is a colorless and transparent gel-like polymer, domestically known as Omnidine and imported as Ingelfahrer, which was once used for filling various soft tissue depressed defects on the body surface, especially for breast augmentation. However, complications such as pain, hard lumps in the breast, infection, mastitis during lactation, displacement of the injected material, and breast swelling have subsequently emerged. It was found that PAHG monomer has neurotoxicity and nephrotoxicity, and it is difficult to remove easily after injection, and it is difficult to deal with complications once they occur. 2006, China Pharmaceutical Administration has issued a document to stop the production, operation and use of PAHG for injection. However, there are still countries where PAHG is used in large quantities for facial and breast fillers. We have accumulated rich experience in the removal of such injections and breast shape reconstruction surgery. Because of the serious breast deformation and possible unevenness of the breast surface after the simple removal of injections, it is very important to perform breast MRI examination before surgery. This examination is helpful in clarifying the distribution of the injected material and the degree of erosion of the surrounding tissues, and in assessing whether silicone gel breast implants can be placed in one stage during surgery. Intraoperatively, with the aid of endoscopy, the injectable and its envelope are removed as much as possible to minimize the risk of the injectable, thus relieving the patient’s fear of it. The breast shape may be improved by the first or second stage of surgery. Patient satisfaction is high and the results are definitive. Considering the toxicity and potential carcinogenic risk of PAHG’s monomer and the frequent complications of patients after injection, we suggest that regardless of discomfort and lumpiness, the injection should be surgically removed as soon as possible and as early as possible, but not by aspiration; aspiration not only fails to remove the injection cleanly, but may also send the injection to different tissue levels through the needle tract, increasing the difficulty of later surgical removal.