IgA nephropathy can cause hematuria and microscopic hematuria under various triggers, upper respiratory tract infection is the most common trigger, for example, some patients with acute tonsillitis will have “soy sauce-colored” or “meat wash-like” hematuria. The most important thing is to actively treat and control the upper respiratory tract infection under the supervision of a specialist, and to drink plenty of water and rest. For those patients who have been diagnosed with IgA nephropathy, during the non-sarcoid hematuria episodes, we advocate proper exercise, physical fitness, healthy living, and active and careful avoidance of potential sources of infection. We all surely want to know what is the prognosis of IgA nephropathy that manifests clinically as hematuria. According to current research results, 10%-20% of patients will obtain complete remission, that is to say, no microscopic hematuria on multiple re-examinations of urine tests after discharge from diagnostic treatment; 10%-40% of patients will experience progression of renal disease, including the development of significant proteinuria, hypertension or significant decline in renal function, while about 2% of patients will develop into renal failure, which is commonly known as “uremia”. Thus, it seems that although IgA nephropathy with clinical manifestations of hematuria is a relatively benign disease process, there is a risk of deterioration, which should neither be completely abandoned nor too agitated and aggressive. In particular, there are some patients who have urinary occult blood +~2+ for many times without other discomfort, so these patients do not need excessive treatment and should not blindly seek medical help to eliminate “hematuria”. In fact, as a patient, the most responsible thing to do for yourself is to avoid excessive tension and worry, maintain a moderate level of self-care, regularly review urine tests and kidney function under the guidance of a specialist, and use regular medication.