Sweet’s syndrome is an acute febrile neutrophilic dermatosis (Dermatology) caused by neutrophilic increase and extensive infiltration of the superficial and middle dermis causing painful raised erythema of the skin with fever and other organ damage, also known as SWEET syndrome. The disease has an acute onset, occurs in summer and autumn, and is common in middle-aged women and older. Influenza-like upper respiratory tract infection, bronchitis, tonsillitis and other precursory symptoms are often present 1-2 weeks before the onset of the disease. The disease is more effective with corticosteroids, and the symptoms can generally be relieved with timely and appropriate treatment. Onset characteristics 1. Rapid onset, mostly flaccid fever. 2. The lesions are usually found on the face, neck and extremities, but rarely on the trunk, with bilateral distribution but asymmetric. 3. The lesions may fade on their own after about 1 to 2 months, leaving no local scarring and atrophy, but recurrent. Prognosis The prognosis is good for patients with simple type, but those with combined proliferative hematologic disease often die of bone marrow failure. Prevention 1. Eliminate and reduce or avoid the development factors, improve the living environment space, develop good living habits, prevent infection, pay attention to dietary hygiene, reasonable dietary allocation. 2. Pay attention to exercise, increase the body’s ability to resist disease, do not overwork and overexert, quit smoking and alcohol. Maintain a balanced psychology and overcome anxiety and tension. 3. Early detection, early diagnosis and early treatment of the original disease, and consider whether it is related to malignant tumor when there are other symptoms. Establish confidence to overcome the disease and persist in treatment.