The first thing you need to consider is that the calluses appear due to long-term wear and tear on the local skin, usually after rest, to avoid continued friction can slowly subside. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. You can be treated through medication, physical therapy and surgery. They can usually be treated with topical salicylic acid, retinoic acid, fluorouracil ointment, imiquimod cream, or topical injections of pinyamycin and bleomycin. You can also use liquid nitrogen freezing, microwave thermal coagulation, laser destruction of warts tissue, or follow medical advice for surgery, direct removal of warts; 2, tendon sheath cysts: may be due to chronic injury to the synovial cavity synovial fluid increases lead to the formation of slowly growing masses. A few tendon sheath cysts can disappear on their own after rest, most cysts persist or have increased in size and need to be treated. Glucocorticoid drugs are available to reduce inflammatory material exudation, and if necessary, surgical treatment is feasible to remove directly; 3. Gout: the callus-like hard lumps on the fingers are called gout stones, which can be treated with febuxostat, allopurinol and other drugs to promote uric acid excretion, so that symptoms can be relieved, and larger gout stones can be removed by surgery.