After laser treatment, correct and reasonable post-operative skin care can reduce post-operative skin discomfort, avoid pigmentation and increase the therapeutic efficacy. Timely ice and wet compresses after laser surgery can relieve skin pain and avoid hyperpigmentation. Laser cosmetic surgery generally uses high energy effect on the skin, after the operation may appear skin redness, mild edema or epidermal breakage, should be immediately cold spray, ice or wet compress mask on the treatment site, do not rub the skin, the general red spot is relatively mild, is the normal reaction to treatment, will slowly fade naturally. At the same time, the timely wet compress after surgery can relieve the pain and discomfort caused by the treatment, reduce skin temperature and avoid pigmentation. After laser treatment, the skin metabolism is accelerated and the skin is prone to dryness. Targeted topical skin care products (such as vitamin E cream, etc.) can increase the water content of the skin stratum corneum, repair the epidermis and reshape the skin barrier. Sun protection after laser treatment is very important. The skin is irritated after receiving laser treatment and UV light stimulates melanocytes within the epidermis to produce a large number of melanin vesicles, which may cause post-operative hyperpigmentation. Therefore, it is very important to protect the skin from the sun after surgery and to use an appropriate SPF/PA value to prevent medium-wave and long-wave UV rays. Shading with clothing and other sun protection is more effective. It is also important to consume less medications and foods with photosensitivity to reduce the possibility of postoperative hyperpigmentation. After CO2 laser treatment, care should be taken to prevent infection. Patients treated with carbon dioxide laser, post-operative treatment local will appear varying sizes of vesicles, ulcers or crust, keep the wound surface dry and topical antibiotic cream, can effectively prevent infection, accelerate the improvement of lesions.