Abnormalities of the liver, gallbladder, spleen and pancreas can cause premature ventricular beats. It can be caused by endocrine pathway and blood circulation pathway, and the primary disease can be the trigger of heart disease if the patient suffers from underlying heart disease. 1. Endocrine pathway: Hepatobiliary, pancreatic and splenic abnormalities, such as cirrhosis, activate angiotensin and renin activation, causing sodium retention, leading to decreased cardiac output and increased cardiac work. This may lead to ventricular premature beats in the heart. 2. Circulatory pathways: in patients with acute necrotizing pancreatitis, there is a severe fluid imbalance, reduced renal blood perfusion leading to electrolyte imbalance, low potassium and sodium can trigger premature ventricular contractions. 3. Patients with underlying heart disease: such as patients with cirrhosis of the liver, causing an imbalance of water and electrolytes in the body. For patients with abnormal heart function, it is easy to induce premature ventricular contractions due to other diseases in the body. Liver, gallbladder, spleen and pancreas abnormalities, the emergence of premature ventricular contractions, it is recommended to go to the hospital in a timely manner to avoid delays in the condition.