In general, when we have a fever, we generally think that our whole body is hot, and our forehead, palms and feet are hot. But sometimes, the body is hot, and the temperature is determined to be feverish, but the hands and feet are cold, and even chills and shivers appear. What is this situation? Then let’s talk about the principle of fever. The general inflammatory response can cause the hypothalamic thermoregulatory center to regulate the rise in body temperature with the aim of suppressing pathogenic microorganisms. The initial stage of fever is the beginning of the central body temperature, mostly in a few hours to reach the peak, this period is called the period of temperature rise. The nervous system of infants and young children is not well developed, and the nerves responsible for vasoconstriction and diastole are prone to dysfunction during the period of temperature rise, resulting in small blood vessels at the ends of infants and young children’s limbs in a state of spasm and contraction (generally adults will also have this situation), so the limbs are cold. Many parents’ first reaction is to “cover”, thinking that covering a sweat can reduce fever. I do not know, the baby sweat glands are not developed, heat dissipation is difficult, cover over also easy to cause “muffled fever syndrome”, serious can cause systemic multi-organ damage. To deal with pediatric fever, according to the different stages of the corresponding treatment: 1, body temperature rise period When the hands and feet are cold, but the armpits, forehead, mouth and other parts of the burning, should be suspected of fever. It is recommended to “keep the end warm”, you can feed warm water, put socks on the baby, or soak the feet in hot water to improve the end circulation. This period will not last long, it indicates that the baby’s body temperature is rising, usually 1~2 hours will occur high fever, parents should pay attention to monitor the temperature changes. 2. The period of persistent high fever suggests “whole body heat dissipation”. If your baby feels hot, you can apply ice to the head, take a warm bath or shower, and drink enough water. When the body temperature exceeds 38.5 degrees, children can take oral antipyretics, such as acetaminophen or ibuprofen. However, guidelines issued by the American Academy of Pediatrics say that fever limits the growth and reproduction of pathogens and is a useful mechanism for fighting infection, and suggest that clinicians and parents should not rush to normalize the temperature of a feverish child, but rather focus on how to make the child comfortable. If the baby is in good spirits, there is no need to use antipyretic drugs immediately, even if the fever is high. Parents should closely observe whether the baby is in serious discomfort, drink more water and replenish electrolytes (such as oral rehydration salts) to avoid dehydration, circulatory disorders or electrolyte disturbances. For babies with a history of febrile convulsions, parents should closely observe temperature changes, actively reduce fever, and use anticonvulsant drugs under the guidance of a doctor if necessary.