Usually shoulder soreness when sneezing is caused by the following reasons: 1. sneezing for upper respiratory tract infections, colds, when the body will stimulate the production of immune response, induced by bacteria, viruses or pathogenic microorganisms infecting the body, when the body will be released by bacteria an inflammatory mediator, such as histamine and leukotrienes and other substances, such substances will lead to peripheral soreness, especially with shoulder soreness is particularly significant. 2. Soreness in the shoulder when sneezing is also caused by excessive force, which involves the joints and ligaments of the shoulder, causing damage to the inter-articular joints and ligaments.3. Sneezing often causes redness, swelling, heat, pain and joint dysfunction in the surrounding local tissues due to bacterial and viral infections, especially at the shoulder joint.