Obstructive bronchiolitis is not self-healing and requires treatment at an early stage to halt the progression of the disease, and there is no effective treatment once irreversible pulmonary fibrosis obstruction has developed. Occlusive bronchiolitis is a rare disease, a clinical syndrome of chronic airflow obstruction caused by inflammatory lesions in small airways. The clinical picture is characterized by persistent cough and wheezing. In severe cases, progressive dyspnea may occur, and in advanced cases, patients may face death due to respiratory failure. Occlusive bronchiolitis is not a self-limiting disease, so the disease is not self-curable. There is no effective treatment. Commonly used clinical treatments include glucocorticosteroids such as methylprednisolone IV, use of macrolides such as erythromycin or azithromycin, and use of leukotriene receptor antagonists such as montelukast. Individuals need to recognize the seriousness of occlusive bronchiolitis and seek prompt medical attention and early intervention if diagnosed with occlusive bronchiolitis to avoid delays.