Inferior vena cava thrombosis may cause cirrhosis. Because the inferior vena cava is the main trunk of venous return to the abdomen, pelvis and lower extremities, once it is blocked by a thrombus, it can be implicated in liver stasis, which can lead to cirrhosis of the liver. The inferior vena cava is the largest venous trunk in the human body. Its main function is to collect venous blood from the lower body back to the right atrium. And it is roughly at the same height as the 4th and 5th lumbar vertebrae, adjacent to the portal vein and the liver. When the inferior vena cava is blocked by a thrombus, it can develop further and affect the blood supply to the heart if the vessel is not unblocked in time. It also affects the blood flow to the portal vein. All these factors will lead to prolonged ischemia and hypoxia of the liver, which will eventually cause necrosis and fibrosis of liver cells thus causing cirrhosis. If a patient has cirrhosis due to inferior vena cava thrombosis, it is important to seek medical treatment in time and actively cooperate with professional doctors.