Autologous fat grafting has a long history and a promising future. In aesthetic plastic surgery, autologous fat grafting can be commonly regarded as improving the appearance of defects by extracting excess fat from the body and transferring it to the area that needs to be filled with fat tissue. Therefore, autologous fat grafting is used to fill facial depressions and deformities, such as facial atrophy, depressed scarring, sunken eyes and face, and deep nasolabial folds; it is also used for cosmetic procedures such as breast augmentation, temporal augmentation, and rhinoplasty. Especially after negative pressure liposuction has been widely used in clinical practice, this grafting procedure is accepted by more and more clinicians and patients. The surgical method of autologous fat transplantation: The patient’s own excess fat is sucked out by negative pressure swelling liposuction with a fine needle, and the sucked out fat is concentrated into fat particles that can pass through a 16-gauge needle after special treatment, and growth factors are added and mixed evenly. Finally, the fat particles are injected into the areas to be filled in a multi-point, multi-tunnel, multi-level radial pattern. Advantages of autologous fat transplantation: 1. Using adipose tissue as soft tissue filling material, its source is abundant and easy to take. Its biocompatibility is far superior to various synthetic prostheses, and is considered a more ideal soft tissue filling material in plastic surgery. 2, autologous fat transplantation in the process of liposuction and fat injection are used fine needle, simple operation, small surgical trauma, fast recovery after surgery, scar is not obvious. 3.After recovery, the fat grafting area has natural appearance, soft handfeel, no rejection reaction and few complications. 4, through the follow-up of a large number of patients who received autologous fat transplantation found that autologous fat transplantation can not only improve the facial contour but also improve the texture and color of the skin in the transplanted area, which may be related to the secretion of various growth factors next to the fat stem cells in the transplanted fat tissue. 5.In addition, autologous fat transplantation can also remove excess fat from the body while repairing defects in appearance, which has the effect of “turning waste into treasure and killing two birds with one stone” and can create a perfect body for the candidates.