At present, there is no scientific evidence to prove that liver protection tablets can achieve the efficacy of removing spots, so liver protection tablets cannot remove spots. Liver protector tablets belong to a kind of Chinese patent medicine, the main function of which is to de-stimulate liver and Qi, strengthen spleen and eliminate food, which can not only protect liver but also treat liver diseases, such as chronic hepatitis and early cirrhosis. As a traditional Chinese medicinal preparation for lowering transaminases, liver protection tablets have been included in the Pharmacopoeia of the People’s Republic of China and are widely used in clinical treatment with good results. If patients have chloasma on their skin, it may be related to their stress, mental tension, or hormonal imbalance, slow metabolism, pigmentation caused by the use of cosmetics of unknown ingredients and excessive ultraviolet radiation. Patients can choose a more authoritative method to help remove the spots, such as can go to the hospital for spot removal laser treatment. The laser does not forcibly remove the pigment, but selectively acts on the deep skin tissue through the epidermis, and absorbs the pigmented tissue into heat energy, producing photothermal effect, so that it is absorbed by pyrolysis or crusted off, thus being able to treat the situation of spots caused by pigmentation, without damage to normal skin. In addition, if the patient’s spots are pigmentation occurring in the epidermis, high concentration fruit acids can also be used to remove the spots, but if the pigmentation is in the dermis, it is not recommended. The principle of acid brushing is to induce aging keratin layer to fall off, accelerate cell renewal and make skin metabolism speed up, and at the same time, it can remove pigmentation of dark spots and acne. However, whether it is photoelectric treatment for melasma or acid brushing treatment, it should be carried out under the guidance of professional doctors, otherwise irregular treatment may aggravate the pigmentation.