The side effects of antithrombotic drugs are mainly due to damage to the digestive tract, while the benefit of antithrombotic drugs is in the treatment of cardiovascular diseases, mainly to relieve luminal narrowing and reduce the accumulation of lipids and cholesterol. The use of antithrombotic drugs may cause damage to the mucosa of the digestive tract as a result of the action of gastric acid, and patients may develop mucosal lesions that persist, such as small erosions that become large erosions and fuse into ulcers. The main complication of peptic ulcer is gastrointestinal bleeding, and the effect of antithrombotic drugs is mainly to prevent blood flow from clotting, so it is more dangerous to have gastrointestinal bleeding. Therefore, after taking antithrombotic drugs, it is necessary to do the appropriate balance treatment, and it is necessary to make an assessment by a specialist and add drugs to protect the gastric mucosa.