Flat warts on eyelids can be removed by physical therapy and medication. Flat warts are a common skin condition caused by human papillomavirus (HPV) and have a high recurrence rate. 1. Physical therapy: the method of liquid nitrogen freezing treatment is to promote the freezing and thawing of warts, edema and necrosis through the low temperature effect of liquid nitrogen. 2. drug treatment: (1) imiquimod cream: research pointed out that the external use of imiquimod cream has a certain efficacy on the viral warts, it should be noted that when applied for a long period of time, it will cause symptoms such as burning sensation, hypopigmentation and pain in the affected area, and when the patient has a serious adverse reaction, the drug should be discontinued in a timely manner. (2) Vitamin A drugs: with the regulation of keratinocyte proliferation, differentiation and inhibition of keratinization, restoration of the role of hyperkeratotic cells. It can be treated by taking oral Avicenna capsule and applying topical retinoic acid cream. (3) Antiviral drugs: the most commonly used is interferon, which can inhibit viral replication and enhance cellular immune function, thus killing and inactivating the virus. It can be treated with oral acyclovir and injection of human interferon alpha-2b. The location of common warts on the patient’s eyelids is special, if the method of freezing treatment is easy to damage the skin, you can take topical medication-based treatment, but the specific treatment measures need to be experienced clinicians according to the patient’s specific situation to choose a different treatment, it is recommended to timely medical treatment.