Antipyretic suppositories are the suppository form of antipyretic drugs. 3-year-old children without fever stuffed with antipyretic suppositories, if removed in time, do not produce adverse reactions. If the time is too long or the dosage is large, there may be anal trauma, restlessness, etc. 1, Because it can inhibit the synthesis of prostaglandins, it can sometimes cause a decrease in blood supply to the gastric mucosa, leading to stress ulcers. 2.Since it needs to be administered through the anus, it can cause anal discomfort after being inserted, and can lead to anal trauma in children if it is more violent when inserted. 3.It also has a certain effect on the central nervous system, which can lead to restlessness and drowsiness in children. Therefore, if children do not have a fever, parents should not let them use fever suppositories at will. For children with fever, the following matters need to be noted when using fever suppositories: 1. They should not be used continuously for more than three days, and if the temperature does not drop after more than three days of continuous use, it is recommended to go to the hospital as soon as possible; 2. The children who are allergic to the ingredients of the fever suppositories, such as ibuprofen and acetaminophen, should be prohibited; 4. If allergic reactions such as hives and eczema occur during use, the use should be stopped promptly.