Fever suppositories are mainly used for children with difficulty in taking medication, coma patients, those with difficulty in taking gastrointestinal tract and those with vomiting symptoms. Clinically used fever suppositories are acetaminophen suppositories, ibuprofen suppositories, dextro ibuprofen suppositories, etc. Among them, dextro ibuprofen suppositories are 1 capsule at a time within 3 weeks of age; 2 capsules at a time above 3 weeks of age; the medication can be repeated after 4 hours. Acetaminophen suppositories are 1 capsule at a time for children over 6 years of age and may be repeated at intervals of 4-6 hours if fever or pain persists. no more than 4 capsules in 24 hours. Ibuprofen suppositories are generally indicated for children 1-3 years old, and can be repeated at 4-6 hour intervals, but no more than 4 times in 24 hours to avoid frequent medication leading to gastrointestinal discomfort and other side effects. Fever suppositories are made of antipyretic drugs with a suitable matrix and are solid preparations for external use, mainly administered by direct anal insertion. In the rectum is directly absorbed into the bloodstream to take effect, so the effect is very fast, usually 30 minutes after the fever will begin to reduce. Before using the suppository, empty the stool as much as possible and wash the anus with water or light salt water. The operator puts on a finger sleeve, lets the patient relax the anus as much as possible, or keep the direction of force of defecation, and gently plugs the suppository into the anus, usually into the anal opening of about 1-4 cm. After inserting the fever suppository, let the patient lie in bed or prone position as much as possible and reduce the activity to avoid the drug from slipping out of the anus. If allergic reactions such as skin rash occur during use, discontinue use promptly.