Lymph nodes are the immune organs of the body and are scattered all over the body in the lymphatic return pathway. Lymph nodes are connected to lymphatic vessels and are important filters of lymphatic return, which is an important barrier to maintain our health. Swollen lymph nodes are very common and can occur in people of any age group and can be seen in a variety of diseases. When we find swollen lymph nodes, it is important to actively identify the cause. There are hundreds of lymph nodes in the human body, and those located on the surface of the body are called superficial lymph nodes. In healthy people, superficial lymph nodes are small, mostly within 0 or 5 cm in diameter, and are not easily palpable. When lymph nodes are enlarged, round, oval or striated nodes can be felt under the skin, especially in the neck, submandibular, supraclavicular fossa, armpit and groin, which are most easily felt. The causes of swollen lymph nodes can be broadly classified into the following three categories: 1. inflammatory reactions: such as acute and chronic lymphadenitis, lymph node tuberculosis, etc.; 2. reactive hyperplasia of lymph nodes; 3. tumor cell lymph node metastasis or lymphoma. It is most crucial to distinguish the different nature of lymph node enlargement. Professional doctors can roughly judge the benignity and malignancy of the lumps from several aspects, such as the length of time they appear, the softness and hardness of the lumps, the presence of pain, whether the lumps become larger and more numerous, and whether there is other general discomfort, etc. However, it is also necessary to consider them comprehensively through various examination methods, among which pathological biopsy of lymph nodes is the most accurate diagnosis method. Lymphoma is a type of systemic hematologic disease, closely related to the immune function of the body, and is treated with chemotherapy as the main treatment. In recent years, significant progress has been made in the treatment of lymphoma, and most of Hodgkin’s lymphoma can be cured, while non-Hodgkin’s lymphoma is less effective than Hodgkin’s lymphoma, but some cases can also be cured. The cause of lymphoma is not well understood and may be the result of many factors interacting with the body. However, certain types of lymphoma may be associated with bacterial and viral infections. Therefore, we should develop good living habits and have regular medical checkups to detect lesions early and treat them early. There are no specific symptoms of clinical manifestations of lymphoma, but if there are unexplained prolonged fever, night sweats, weight loss or sudden painless enlargement of lymph nodes, you should go to the hospital as soon as possible.