Lumbar disc herniation and sciatica can take the following types of drugs: First, non-steroidal anti-inflammatory and analgesic drugs: such as celecoxib capsules, loxoprofen sodium tablets, Ankangxin, pau taisong, ibuprofen extended-release capsules, such drugs are the first-line clinical drugs, which can relieve inflammation and reduce pain without causing serious side effects. Second, neurotrophic drugs: such as B vitamins, including vitamin B1, vitamin B6, vitamin B12, adhere to long-term oral intake, can promote the recovery of nerve conduction function and reduce sciatic nerve pain. Third, Chinese medicines: such as Cao Wu Jia Su tablets, Hu Li San capsule, Pan Long Qi tablets, Palsy capsule, etc. These drugs can open the meridians and improve the clinical symptoms of lumbar intervertebral disc herniation and sciatic nerve pain. Generally, oral intake of the above types of drugs can bring about significant relief of clinical symptoms.