Hepatitis B is a progressive disease that can escalate to cirrhosis and liver cancer at any time as the hepatitis B virus continues to replicate at a high rate. In order to delay the progression of the disease, patients should establish a global view of treatment, active antiviral effective management of the disease. I. Early treatment to delay the progression of chronic hepatitis B development of cirrhosis, the lightest, in fact, only a few small nodule formation of severe hepatitis, known as early cirrhosis. Early cirrhosis caused by hepatitis B is reversible after antiviral treatment, and very most of them can take off the cap of cirrhosis. However, early cirrhosis is difficult to diagnose by ultrasound and CT, and can only be detected by liver aspiration. For mild to moderate cirrhosis after hepatitis B and C, although antiviral treatment cannot reverse the course of cirrhosis, it can delay its development very well, on the contrary, if the replication of hepatitis virus is not controlled, the course of cirrhosis will be faster. In short, the earlier the intervention of the cause, the greater the chance of reversing early cirrhosis or delaying its development. Second, late treatment, prevention and treatment of complications If cirrhosis reaches an advanced stage before intervention and treatment, the overall effect is hardly satisfactory. The main goal is to prevent and treat complications, including control of portal hypertension, prevention of bleeding from ruptured fundic-esophageal veins, treatment of ascites, hypoproteinemia, etc. A series of serious complications will occur in the late stage of cirrhosis, and the treatment is rather passive. At this time, a large area of irreversible fibrosis has occurred in the liver, and it is difficult to treat cirrhosis from the etiological point of view. Liver transplantation is generally used for end-stage liver disease for which conventional medical and surgical treatment is ineffective. These include: irreversible ascites; portal hypertension with upper gastrointestinal bleeding; severe hepatic impairment (Child class C); hepatorenal syndrome; progressive hepatic encephalopathy; and cirrhosis complicated by hepatocellular carcinoma. Liver transplantation is the last resort in the treatment of end-stage cirrhosis, but liver sources are often scarce and costly. Therefore, it is crucial to control the disease in its early stages and should not be delayed until it needs to be decompensated, when it is too late. In addition to removing the causes of liver damage, cirrhosis still has a chance to be controlled in the early stage. Patients with alcoholic cirrhosis must stop drinking, and cirrhosis caused by viral hepatitis should be treated regularly and followed up regularly.