Sweat spot is pityriasis, a chronic infectious skin disease mainly involving superficial layer of epidermis caused by Malassezia, which occurs in young adults, often recurrent, with light brown spots and hypopigmented spots with scales as the characteristic lesions, often involving the chest and back and other parts with more sebum secretion. At present, the treatment for pityriasis pilaris is mainly focused on the external and internal use of anti-fungal drugs. If the lesions are small in size, ketoconazole lotion or selenium disulfide lotion can be considered for cleansing, together with antifungal ointment, commonly naftifine ketoconazole cream combined with adapalene gel treatment. It is particularly indicated for patients with more thickly scaly lesions and markedly oily skin types, and for patients who are unsuitable for or unwilling to take oral antifungal preparations. Topical adapalene accelerates the shedding of scales and increases the penetration of other topical drugs into the stratum corneum, thus achieving a synergistic effect. On the one hand, it reduces the pathogenic bacteria, and on the other hand, it promotes the penetration of naftifine ketoconazole cream in the stratum corneum, increasing the accumulation of drugs entering and remaining in the affected stratum corneum, further removing the deeper Malassezia in the stratum corneum. The therapeutic effect continues 2-4 weeks after discontinuation of naftifine ketoconazole cream. If patients have recurrent episodes or large lesions, they can be treated with oral itraconazole, ketoconazole, fluconazole and other azoles under the guidance of a professional physician.