Provide the 1995 Japanese Ministry of Health and Welfare DPB diagnostic criteria.
1. Persistent cough, sputum and shortness of breath after activity;
2.Intermittent large stalls can be heard in the chest
3, diffuse small nodular shadow in both lungs on chest imaging, increased total lung volume, bronchial dilatation in both lower lungs, central nodules in HRCT lobules or “tree tooth sign”;
4.Pulmonary function FEV1%<70%,PAO2<10,67KPA;
5, serum condensation set test >1:64 or positive antibodies to mycoplasma;
6, combined with a history of chronic sinusitis.
If the above 6 items are met, DPB can be diagnosed clinically.
New criteria for diagnosis of DPB by the Ministry of Health and Welfare of Japan in 1998.
Required conditions:
1, persistent cough, sputum and shortness of breath after activity;
2, combined with a history of chronic sinusitis.
3, diffuse nodular shadow in both lungs on chest imaging, increased total lung volume, bronchial dilatation in both lower lungs, central nodules in the lobules of HRCT or “tree tooth sign”;
Reference conditions:
1, intermittent large stalls can be heard in the chest
2, pulmonary function FEV1%<70%, PAO2<10,67KPA;
3.Serum condensation set test >1:64 or positive for mycoplasma antibody;
(1) Confirmation of diagnosis: meeting all the necessary conditions + 2 or more reference conditions.
(2) General diagnosis: some of the above-mentioned conditions are required.
(3) Suspicious diagnosis: 1 or 2 of the required conditions.
Treatment.
1. Erythromycin: Erythromycin 400mg or 600mg orally daily for 6 months or more in initial cases. For cases with progressive disease, the drug can be continued for more than 2 years.
2.Glucocorticoid: usually 1~2mg kg-1 d-1, after the symptoms are relieved, the dosage will be gradually reduced. The duration of treatment is at least 6 months, and can be used in conjunction with macrolides throughout the course of treatment, and gradually reduce the dosage.
Other measures include antibiotics, expectorants, bronchodilators, treatment of paranasal sinusitis, etc.