Last week, a post-trigeminal herpetic neuralgia from Mudanjiang City was discharged from our pain department with a smile on her face. The reason why the patient flew all the way from Mudanjiang to Guangzhou to seek help was because the physicians of several hospitals had followed the treatment for trigeminal neuralgia after the disease, which not only failed to achieve the goal, but also led to the expansion of the damage. In fact, there is a difference in the nature of nerve damage between post-trigeminal herpes zoster neuralgia and trigeminal neuralgia, and the abnormal changes in the sympathetic nervous system make conventional radiofrequency treatment often counterproductive. After more than two weeks of treatment to promote nerve damage repair, the patient’s damage was significantly reduced in extent and the pain level was relieved by more than 80%. The patient was discharged from the hospital with ozone to consolidate the intervention and was informed of post-discharge precautions to reduce the possibility of recurrence. The patient and his family returned to Mudanjiang satisfied. We hereby hope that fellow physicians treating patients with post-trigeminal herpes zoster neuralgia will refrain from using radiofrequency destructive treatments for trigeminal neuralgia.