The main reasons for twitching in sleep are as follows: 1. Physiological factors, if the usual life is more stressful, mental tension and after excessive exercise can be muscle twitching symptoms at night when sleeping, but this is often transient, can be effectively relieved after removing the trigger, do not need to worry too much and treatment. 2. Hypocalcemia, low calcium will make the sensitivity of nerve cells increased, also This is one of the common clinical diseases that cause convulsions, mainly caused by abnormal neuronal discharges in the brain, which need to be diagnosed according to clinical performance and EEG examination. The main treatment is to take anti-epileptic drugs, such as sodium phenytoin and sodium valproate.