Case sharing: Two days after his birth, newborn Gogo showed up with cyanotic lips and cried constantly while feeding. 10 days old, he was brought by his parents to a large hospital pediatric department for examination and diagnosed with congenital heart disease (congenital heart disease), and the situation was very serious. According to the survey, China’s annual new children with congenital heart disease about 200,000, that is, every 10 minutes there are 3 newborns with a defective heart to the world, and pediatric congenital heart disease is the disease in the higher mortality rate, especially the newborn with congenital heart disease if not timely medical treatment mortality is very high. Precardiac disease does not usually heal on its own, but for ventricular defects less than 0.5 cm, there is a possibility of recovery. Most precardiac diseases require surgery, and it is better to treat them at the age of 2 to 5 years so that they do not affect the child’s psychological and physical development. However, some complex precordial diseases require early surgery and are treated according to the recommendations of the cardiac surgeon, regardless of age. It is important to prevent colds when the cold comes! Children with precocious heart must usually pay attention to the prevention of respiratory infections because of congenital anomalies in children with congenital heart disease such as arteriovenous ductus arteriosus, atrial and ventricular septal defects, which generally have poor general development and nutritional status and are prone to colds, and should be actively treated once respiratory infections occur. Some children with severe congenital heart disease may have purple lips, nails and skin, especially when they exercise or cry. When this happens, rest and avoid strenuous exercise and crying to avoid heart failure, infective endocarditis or thromboembolism, etc. Antibiotics should be used to prevent infective endocarditis before and after any other surgery (including tooth extraction, tonsillectomy, etc.). Prevention during pregnancy is the main tool to reduce the incidence of precocious heart disease! To prevent and reduce the chances of precardiac disease, it is important that women during pregnancy, especially those within the third trimester of pregnancy, live in good condition. During this period, pregnant women should prevent viral and parasitic infections, especially to prevent the occurrence of many infectious diseases such as colds; have a reasonable diet and exercise to strengthen the body resistance. At the same time, pregnant women during pregnancy should not take drugs indiscriminately. For example, some pregnant women think that a cold or fever is a minor illness, so they go to the pharmacy to buy some adult drugs to take, which can have some potential harm to affect the fetus in the womb. There are also risks associated with an advanced maternal pregnancy because there are genetic factors that can affect the genes and chromosomes of the fetus, thus increasing the chances of the newborn developing precocious heart disease. Precocious diseases are divided into simple and complex, and the timing of treatment surgery is different for different types of children with precocious diseases, but it is important to seek medical attention in a timely manner so as not to delay the condition and miss the treatment period. Children with simple precardiac disease do not have many obvious clinical manifestations and can be rehabilitated by interventional therapy or cardiac surgery. If a newborn has symptoms such as purple lips or nails, feeding difficulties, crying easily, and not growing, it is important to have a timely examination, as these may be early clinical manifestations of complex precardiac disease, and early detection and treatment are especially important.