Low or no Lactobacillus indicates the presence of vaginitis or the occurrence of an imbalance in the intestinal flora. Lactobacillus is a Gram-positive bacterium found mainly in the oral cavity, intestinal tract and vagina, and is thought to be protective in the intestine and vagina. Patients with vaginitis or imbalance of intestinal flora may have little or no Lactobacillus. 1. Vaginitis: common in bacterial vaginitis, normal vaginal flora is dominated by Lactobacillus, which keeps the vagina in a normal state with weak acidic pH by producing lactic acid. If there is little or no lactobacillus, it causes pH to rise, resulting in an imbalance in the vaginal micro-ecological environment, which provides conditions for bacteria to breed, thus easily leading to bacterial vaginitis. Patients may secrete thin, fishy smelling leucorrhea from the vagina, and may also experience mild vulvar itching or burning sensation, with symptoms worsening after sexual intercourse. It is recommended that patients with these symptoms seek medical attention to improve the relevant tests, make a clear diagnosis and carry out active treatment. 2. Imbalance of intestinal flora: Lactobacillus present in the intestinal tract can help inhibit the growth of harmful microorganisms and pathogenic bacteria inside the intestinal tract, and also maintain the balance of the intestinal flora. Therefore, if Lactobacillus is low or absent, it usually indicates an imbalance of intestinal flora. Patients mainly present with a series of digestive symptoms such as indigestion, abdominal pain, diarrhea and constipation. It can be improved by taking drugs such as lactobacillus tablets. If the symptoms are serious, other gastrointestinal diseases should also be alerted and timely medical treatment is recommended.