Facial nerve spasm, also known as facial muscle spasm, is a paroxysmal, involuntary and irregular muscle spasm on one side of the face without any other signs of neurological damage. The onset is mainly in middle-aged women. The onset is usually a paroxysmal small twitch of the lower eyelid orbicularis muscle that gradually extends downward to the buccinator, orbicularis oris and broad neck muscles. The degree of spasm varies. The spasms increase when nervous, emotional or tired. When quiet or asleep, the spasm is reduced or disappears. In some severe cases, facial twitching may affect half of the facial muscles. The twitching is mostly confined to one side and is very rare on both sides. The disease is a chronic progressive development that does not usually resolve spontaneously, and some patients suffer lateral muscle paralysis and atrophy in the late stages, and the twitches appear to cease. At the beginning of the disease process, when the facial muscle spasms are limited to the orbicularis oculi, care should be taken to distinguish them from blepharospasm, which does not usually spread to the face and is usually bilateral. When facial muscle spasms are accompanied by other cranial nerve injuries, or limb dysfunction, or involuntary limb movements, intracranial injuries should be considered and require treatment in a hospital. Facial muscle spasms are mainly treated with medications, such as phenytoin sodium, Librium, Valium, and so on, and with physical therapy, and the symptoms of mild patients can be slightly relieved after treatment. In severe cases, when medication is ineffective, facial nerve decompression surgery may be performed. (The specific medications mentioned in the text should be prescribed based on an interview with a specialist.)