The inability to move the thumb of diabetic patients may be caused by ischemia, necrosis and bone deformity of the finger ends, etc. The treatment mainly includes hypoglycemic treatment, nutritive neurovascular treatment and surgical treatment. 1, hypoglycemic treatment: diabetic patients need to follow the medical advice to use hypoglycemic drugs, such as metformin, acarbose, etc., or subcutaneous injection of insulin. Dietary control of calories, avoiding high sugar foods, appropriate exercise, weight control. 2、Nutritional neurovascular treatment: If the blood sugar is not well controlled for a long time, the peripheral nerves and microvessels of the limbs will be damaged to different degrees, and ischemia and necrosis may occur in the finger ends, so it is necessary to take medicines to protect the nerves and blood vessels to improve the symptoms according to the doctor’s prescription. 3、Surgical treatment: if necessary, you can choose vascular bypass surgery and other surgeries to restore the blood flow of the fingertips, or surgery to correct the bone deformity. About diabetic patients can not move the thumb of the treatment program more, there is a certain degree of individual variability, it is recommended to consult a doctor in a timely manner, choose the appropriate treatment program.