Intermuscular vein thrombosis of the calf is recommended to have a small amount of exercise under the supervision of a doctor. Calf interosseous vein thrombosis is one of the more common types of deep vein thrombosis in the lower extremities, and is commonly seen in post-surgical patients as well as patients who have been bedridden for a long period of time. Patients with intermuscular vein thrombosis of the calf routinely need to be braked and relieved of symptoms, including bed rest, elevation of the affected limb, the calf position should be 20-30cm above the heart level. the purpose of braking is mainly to prevent the dislodgement of blood clots leading to the occurrence of pulmonary embolism. However, during the treatment period, if the condition permits, patients can wear compression stockings or elastic bandages to get up and carry out activities and moderate exercise, during which patients should strictly follow the doctor’s instructions to avoid blind activities on their own. Intermuscular vein thrombosis in the calf should be treated as soon as possible, otherwise the thrombus may continue to spread to form a large embolism, causing obvious swelling of the lower limbs, or even thrombus dislodgement resulting in more serious pulmonary embolism, leading to respiratory distress and endangering life.