If the headache is a cold, you can take the following major types of drugs: 1. You can take non-steroidal anti-inflammatory drugs. For example, acetaminophen, compound aminobarbital, indomethacin class, salicylic acid class of drugs can relieve the headache caused by cold. The representative drugs of this kind are Celebrex, Fenbuterol, Somitol and other drugs, all of which can treat the above-mentioned conditions. 2, the headache caused by the cold should also be treated at the root, that is, the treatment of the cause. If it is a viral cold, it is recommended to take oseltamivir, and if it is a bacterial cold, you can take drugs such as levofloxacin, roxithromycin, azithromycin, etc., all of which can treat headaches caused by colds. 3. headache caused by cold.