Vascular plaque usually occurs in the large and medium arteries throughout the body, including the aorta, carotid and extremity arteries, and visceral arteries. In general, internal carotid artery vascular plaques are more common and easier to detect. Coronary artery vascular plaques can often cause angina pectoris, and myocardial infarction can occur after rupture and bleeding. Vascular plaques can also occur in both lower limbs, which can cause limb ischemia and activity impairment.