There is no such thing as the fastest way to remove vascular plaque. The formation of plaque in the blood vessels generally cannot be eliminated, and the only way to alleviate the condition at present is through medication or surgical treatment. Vascular plaque is related to the deposition of lipids in the lining of arterial vessels. For patients with high blood lipids, drugs such as atorvastatin and simvastatin can be considered to lower the levels of cholesterol and triglycerides in the blood and slow down the rate of vascular plaque formation. Antiplatelet therapy to prevent thrombosis and aggravation of the condition is commonly used with oral medications such as aspirin and clopidogrel. If plaque formation of thrombus leads to narrowing or blockage of the lumen, thrombolytic drugs can be used, such as streptokinase, alteplase and so on. If plaque is blocking the entire vessel, it can be restabilized and blood flow restored by stenting, which then props up the vessel to support the plaque that has been dislodged. The above medications are for reference only and specific dosages should be followed as prescribed by your doctor. When vascular plaque occurs, it is recommended to seek timely medical attention, follow the doctor’s instructions for further examination, and with the help of the doctor, carry out targeted treatment.